The immune privilege of tissue engineered articular cartilage derived from mouse adult mesenchymal stem cells and the potential of tissue engineered cartilage as a gene delivery method Chapter 1 Stem cell biology 1.1 Categorization of stem cells Stem cells are generally defined as cells possessing the following 3 characteristics: (1) self-renewal, (2) the ability to […]
The Stem Cell Debate: Ethical Questions The story for the year 1997 was the sacred. We fear a Promethean blunder. We fear that our own human hubris will violate something sacred in our nature; and we fear that nature will retaliate with disaster. To protect ourselves from a possible Promethean blunder by science, we are […]
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Get startedHYDROGELS FOR WOUND HEALING APPLICATIONS Abstract This chapter discusses about the hydrogels both natural and synthetic that can be used for wound healing applications. Also it discusses briefly about the various novel techniques that have been developed recently. Keywords: Hydrogels; Chitosan, Antimicrobial; Grafting; Blending; Wound dressing; Wound healing; Gene therapy, Stem cell therapy, Skin Engineering, […]
Characterisation of prostate cancer stem cells Abstract Background Advances in the study of cancer cells with stem cell characteristics may enable the development of new and improved cancer therapies. Stem cell marker expression can be investigated by QPCR and this sensitive method has been used to characterise prostate cancer stem cells. Methods Prostate cancer cell […]
Animal testing has been a part of pharmaceutical, cosmetic, and toxicity research for many years. Many innocent animal lives are being taken for the sake of science, when it is unnecessary to do so. Scientists have had the knowledge of human embryonic stem cells for research for years and yet they decide to use sentient […]
The topic of a human embryonic stem cell research (HESCR) has been a controversial issue since late 1990s. Opponents of HESCR have been arguing that it is not only a waste of federal funding, it is also against a moral code. Former President George W. Bush, a republican, placed a ban in HESCR due to […]
Back pain is one of the most common complaints doctors hear from their patients. While there are many treatments available, stem cell treatment for back pain is quickly becoming a viable option. Stem cells are able to help rebuild joint cartilage, tendons, ligaments and muscle tissue, all of which help strengthen the back and relieve […]
Have you ever wondered if it is possible to cure cancer, have genetically related babies from same-sex parents, completely eradicate mosquitoes, resurrect an extinct species, or even insert a GIF into bacteria and have the bacteria replicate the GIF? With technology becoming more advanced by the hour, increasing possibilities are arising. In 1993, certain segments […]
Adult stem cells are the undifferentiated cells that are involved in the maintenance, renewal, and repair of various tissues and organs. These stem cells are found in particular niche in a tissue or an organ where they remain undifferentiated and are activated to undergo division and differentiation to maintain the tissue or when activated by […]
The heart is one of the most essential organs in the human body. It is what keeps almost every organism alive. However, recent studies have found that heart disease is the leading cause of death in America, creating a problem for the medical communities that are trying to save lives. Not only is it nearly […]
Stem cell therapy has been a controversial matter in the media for years.Just recently there is evidence stem cell therapy can be a potential treatment for chronic pain. Chronic pain is pain lasting 6 months or longer and is recurrent.An estimated 30.7% of Americans suffer from chronic pain in today’s society(Marie Csete, 2014).At the height […]
Stem cells were accidentally discovered by two scientist’s researching in the Ontario Cancer Institute, Till & Ernest McCulloch examined an anomaly during a study they were conducted on the effects of radiation on mice. The mice were exposed with an ample amount of X-rays to kill them in 30 days if they did not obtain […]
As the world advances in medical technology, there is developing research on the focus of Stem Cell therapy. Countries around are using government funds to boost their programs and be competitive in the global innovation race. However, the United States (U.S.) created laws that limits the governments’ funding towards Stem Cell research programs. These laws […]
Abstract Stem cells are literally the gods of all cells. They have the potential to develop into so many different types of cells within the body. For many untreatable neurodegenerative disorders, stem cell research offers great promise and hope for a cure to these progressive diseases. Here we discuss what a stem cell is and […]
The genome editing using engineered nuclease has strategically transformed the idea of gene therapy for monogenic diseases including in hematopoietic stem and progenitor cells (HSPCs) (Osborn et al., 2016; Yu et al., 2016). The genome editing technology enables to create a site specific double-strand break (DSB) by the engineered nucleases that programmable triggering the cell’s […]
This proving iPSCs are a better option because they have similar findings as the mouse model with more of an advantage linking to the human patients since these iPSCs were from human patients with the disease. Overall the end goal is to find a drug that slows the progression or stops the neurodegeneration in humans […]
For centuries, past scientific discoveries have paved the way for future innovations. In addition, they have also positively impacted and influenced the medical and science field. A new discovery that scientists are looking into are Embryonic Stem Cells”otherwise known as ES Cells. While scientists are rushing to observe and experiment with ES Cells, many support […]
Wouldn’t it be great if we are able to manipulate cells for our own welfare? Stem cells can help victims who are diabetic, paralyzed, and even burn victims. Stem cells are helpful for victims who have had third degree burns. It can help make insulin for people that are diabetic, and assist patients that are […]
Stem cells are undifferentiated cells of multicellular organisms. Specifically embryonic stem cell are pluripotent, meaning they can create several different types of cells. With this new knowledge, biomedical research has ascended to new levels. To get embryonic stem cells biologists first produce via vitro fertilization, which is where an egg and sperm are combined outside […]
Drug screening and induced pluripotent stem cells are still fairly new components in the scientific world but continue to expand as more research is being conducted. Just in 2006 induced pluripotent stem cells (iPSCs) branched off of embryonic stem cells that were discovered in 1998 (6) and since iPSCs lack ethical issues, they have been […]
Human embryonic stem cells are unspecialized cells that can turn out to be any of the 200+ particular or separated cells that complete the particular elements of the body, for example, skin, blood, muscle, and nerve cells. Researcher trust that human embryonic undifferentiated organisms have a boundless potential in making therapeutic medicines that supplant lost […]
Abstract Stem cells are literally the gods of all cells. They have the potential to develop into so many different types of cells within the body. For many untreatable neurodegenerative disorders, stem cell research offers great promise and hope for a cure to these progressive diseases. Here we discuss what a stem cell is and […]
The ethics of using stem-cell research has become a great issue in the past few years. The advocates for both sides of the issue have many reasons to conduct the research or not to. This issue arose after the successful cloning of Dolly the sheep in 1996. After this, the question Can we use stem-cell […]
Biomaterials for stem cell delivery in cardiovascular regeneration Cardiovascular diseases (CVDs) are disorders of the heart and the blood vessels which are the leading cause of morbidity and mortality worldwide and related with 31% global deaths every year.[64] Although pharmacological and interventional treatments are well-established to relief the symptoms and complications (e.g. arrhythmia) to prevent […]
What if I told you that researchers could cure diseases like Diabetes, heart disease, Alzheimers or Parkinsons? The chances of you being on board with ending these horrible diseases that millions of people suffer from each year is extremely high. The cures of these diseases are the potential result of embryonic stem cell research. The […]
This section offers a summary regarding the background of the topic concerning how Stem Cell Research and treatment works and its purpose together with application in the real world. The stem cells are usually capable of developing into different cell types both in the embryonic period as well as during growth. The stem cells can […]
In this paper I will mainly focus on the effects of stem cell injections on skeletal muscle injures in mice, this is because those types of muscle injuries are extremely common. Skeletal muscle is a highly specialized tissue made up of non-dividing, multi-nucleated muscle fibers, which contract to generate force in a controlled and controlled […]
Introduction: Research Problem Dolly the sheep was the first big breakthrough in stem cell research during the 1990s, but it remains a contentious subject today. From synthetic biology of gene cloning to gene editing and even embryonic research, the ethics mean weighing potential benefits against the costs. There is also a need to separate out […]
More than thirty years ago, in 1981, scientists were able to successfully extract embryonic stem cells from mice, effectively opening a door to new discoveries in scientific and medical fields. Stem cells are unspecialized cells meaning that they have no set function in the body. Scientists have also found ways to influence these cells into […]
Regenerate the Vascular Tissue Blood vessels composed of endothelial cells and mural cells play key roles in tissue regeneration and repair by serving as conduits to deliver oxygen and nutrients to injured and newly-formed tissues.[88] Many CVDs such as coronary artery disease (CAD) and peripheral vascular disease (PAD) are resulted from the loss of vascular […]
