The heart is one of the most essential organs in the human body. It is what keeps almost every organism alive. However, recent studies have found that heart disease is the leading cause of death in America, creating a problem for the medical communities that are trying to save lives. Not only is it nearly impossible for doctors to cure a damaged heart for a long term, it is also costly and leads to more surgeries just to keep the […]
Regenerate the Vascular Tissue Blood vessels composed of endothelial cells and mural cells play key roles in tissue regeneration and repair by serving as conduits to deliver oxygen and nutrients to injured and newly-formed tissues.[88] Many CVDs such as coronary artery disease (CAD) and peripheral vascular disease (PAD) are resulted from the loss of vascular supply leading to organ failure. Regeneration of blood vessels can be generally divided into two major aspects: the neovascularization in ischemic tissues, and repairing of […]
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Get help with your assigmentIn this paper I will mainly focus on the effects of stem cell injections on skeletal muscle injures in mice, this is because those types of muscle injuries are extremely common. Skeletal muscle is a highly specialized tissue made up of non-dividing, multi-nucleated muscle fibers, which contract to generate force in a controlled and controlled manner,which account for up to half the mass of the human body. However, effective muscle function is both mechanically and energetically demanding, making this tissue […]
More than thirty years ago, in 1981, scientists were able to successfully extract embryonic stem cells from mice, effectively opening a door to new discoveries in scientific and medical fields. Stem cells are unspecialized cells meaning that they have no set function in the body. Scientists have also found ways to influence these cells into becoming tissues, organ-specific cells, and other specialized cells. In addition to this, they are also capable of replenishing themselves through cell devision. However, this research […]
Bethesda, MD. Stem Cell Basics I. National Institutes of Health, U.S. Department of Health and Human Services, 2016, https://stemcells.nih.gov Accessed 25 November 2018 The source gives an introduction to stem cells, explaining what they are and their importance. The source continues to go into information on different types of stem cells, including where they are located and what they are used for. The source also includes the uses of stem cells and obstacles that doctors face while using them. This […]
Stem cells were accidentally discovered by two scientist’s researching in the Ontario Cancer Institute, Till & Ernest McCulloch examined an anomaly during a study they were conducted on the effects of radiation on mice. The mice were exposed with an ample amount of X-rays to kill them in 30 days if they did not obtain a transplant of bone marrow cells. The mice were also vaccinated with a fluctuating number of cells in order for the researchers to conclude how […]
The topic of a human embryonic stem cell research (HESCR) has been a controversial issue since late 1990s. Opponents of HESCR have been arguing that it is not only a waste of federal funding, it is also against a moral code. Former President George W. Bush, a republican, placed a ban in HESCR due to its ethical nature as well as inhibiting the use of federal funding. However, his successor, President Barack Obama, a democrat, lifted the ban allowing federal […]
Back pain is one of the most common complaints doctors hear from their patients. While there are many treatments available, stem cell treatment for back pain is quickly becoming a viable option. Stem cells are able to help rebuild joint cartilage, tendons, ligaments and muscle tissue, all of which help strengthen the back and relieve pain. Doctors are even able to take stem cells from the patient and inject them into the back, allowing the patient’s body to heal itself. […]
Biomaterials for stem cell delivery in cardiovascular regeneration Cardiovascular diseases (CVDs) are disorders of the heart and the blood vessels which are the leading cause of morbidity and mortality worldwide and related with 31% global deaths every year.[64] Although pharmacological and interventional treatments are well-established to relief the symptoms and complications (e.g. arrhythmia) to prevent sudden cardiac death, these strategies mainly delay the death with a poor long-term prognosis rather than provide functional recovery of cardiovascular system.[1b, 65] Due to […]
What is your personal moral standpoint on stem cell research? In today`s society, it is hard to differentiate between morally correct and politically correct, the line is often blurred in view. The intent of this research is to further scientific advancements but the price to pay is stepping across a couple personal boundaries. Angela Campbell wrote an interesting article for the American Journal of Law and Medicine in Boston outlining the biggest controversial topic of today pointing out, Worldwide, legislators […]
Human embryonic stem cells are unspecialized cells that can turn out to be any of the 200+ particular or separated cells that complete the particular elements of the body, for example, skin, blood, muscle, and nerve cells. Researcher trust that human embryonic undifferentiated organisms have a boundless potential in making therapeutic medicines that supplant lost or harmed cells offering want to individuals that experience the ill effects of tumor, diabetes, cardiovascular illness, spinal-rope wounds, and numerous different issue. As per […]
Introduction: Research Problem Dolly the sheep was the first big breakthrough in stem cell research during the 1990s, but it remains a contentious subject today. From synthetic biology of gene cloning to gene editing and even embryonic research, the ethics mean weighing potential benefits against the costs. There is also a need to separate out individual from societal benefits. Unmistakably, the chance to potentially fix hereditary issues can be tempting. General morals and ethics allow public opinion to sway back […]
As the world advances in medical technology, there is developing research on the focus of Stem Cell therapy. Countries around are using government funds to boost their programs and be competitive in the global innovation race. However, the United States (U.S.) created laws that limits the governments’ funding towards Stem Cell research programs. These laws created by President George W. Bush have stopped the growth of U.S. Medical technology in comparison the world. According to Bush his main reasoning to […]
Abstract Stem cells are literally the gods of all cells. They have the potential to develop into so many different types of cells within the body. For many untreatable neurodegenerative disorders, stem cell research offers great promise and hope for a cure to these progressive diseases. Here we discuss what a stem cell is and the basic functions, how it can be used to help alleviate one of the largest symptoms of Alzheimer’s disease, and research of stem cells on […]
Stem cells are undifferentiated cells of multicellular organisms. Specifically embryonic stem cell are pluripotent, meaning they can create several different types of cells. With this new knowledge, biomedical research has ascended to new levels. To get embryonic stem cells biologists first produce via vitro fertilization, which is where an egg and sperm are combined outside of the body, isolated at blastocyst stage, and are finally grown in culture. Embryonic stem cells are not regarded as native pluripotent stem cells, which […]
To delay or perhaps, reverse aging is a topic that occupies the mind of many researchers. Stem cells are tools that help study aging because : they divide and renewing themselves for long periods,they differentiate into different cell types as they are initially unspecialized. These cells are immortal, they do however decrease in functioning as years go by and we age. Two vivid examples of this are: melonocyte stem cells which give rise to he pigment of our hair, but […]
Adult stem cells are the undifferentiated cells that are involved in the maintenance, renewal, and repair of various tissues and organs. These stem cells are found in particular niche in a tissue or an organ where they remain undifferentiated and are activated to undergo division and differentiation to maintain the tissue or when activated by disease or disruption. Skin undergoes constant renewal and it is crucial to study the dynamic pathways and key regulators involved at the transcriptional level in […]
This section offers a summary regarding the background of the topic concerning how Stem Cell Research and treatment works and its purpose together with application in the real world. The stem cells are usually capable of developing into different cell types both in the embryonic period as well as during growth. The stem cells can undergo self-renewal and may be induced to develop into an organ or tissue-specific cells. Current stem cell research together with the therapy is based on […]
As cancers are heterogeneous, drug discovery efforts are aiming to increase patient survival and will surely need to consider the plasticity of cancer cells (Singh and Settleman, 2010). Cancer stem cells have a higher intrinsic resistance to chemotherapy than do normal cancer cells, and may be the source of post-therapy relapse (Thomas; et al, 2014). New agents were discovered as anticancer drugs to destroy cancer stem cells that are resistant to chemotherapy. This review paper will focus on some important […]
Have you ever wondered if it is possible to cure cancer, have genetically related babies from same-sex parents, completely eradicate mosquitoes, resurrect an extinct species, or even insert a GIF into bacteria and have the bacteria replicate the GIF? With technology becoming more advanced by the hour, increasing possibilities are arising. In 1993, certain segments of DNA were discovered, called CRISPR (Clusters of Regularly Interspaced Short Palindromic Repeats). Twelve years later, Cas9, an enzyme responsible for separating areas of DNA […]
The genome editing using engineered nuclease has strategically transformed the idea of gene therapy for monogenic diseases including in hematopoietic stem and progenitor cells (HSPCs) (Osborn et al., 2016; Yu et al., 2016). The genome editing technology enables to create a site specific double-strand break (DSB) by the engineered nucleases that programmable triggering the cell’s endogenous repair machinery to edit the genome in a site-specific manner via the non-homology end joining repair (NHEJ) and the homology directed repair (HDR) mechanisms(Branzei […]
This proving iPSCs are a better option because they have similar findings as the mouse model with more of an advantage linking to the human patients since these iPSCs were from human patients with the disease. Overall the end goal is to find a drug that slows the progression or stops the neurodegeneration in humans for this specific disease and being able to test the drugs out in human cells rather than animal cells would have more advantages. Another important […]
Drug screening and induced pluripotent stem cells are still fairly new components in the scientific world but continue to expand as more research is being conducted. Just in 2006 induced pluripotent stem cells (iPSCs) branched off of embryonic stem cells that were discovered in 1998 (6) and since iPSCs lack ethical issues, they have been used to differentiate from stem cells such as from a diseased patient to motor neurons. But are these reprogrammed differentiated cells as reliable as embryonic […]
For centuries, past scientific discoveries have paved the way for future innovations. In addition, they have also positively impacted and influenced the medical and science field. A new discovery that scientists are looking into are Embryonic Stem Cells”otherwise known as ES Cells. While scientists are rushing to observe and experiment with ES Cells, many support the use because of the benefits, while others strongly oppose. ES cells are proven to drastically benefit the medical industry, but the morality of the […]
A Step In a New Direction Ethicality, research, possibility. When the subject of human cloning is brought up most tend to think of the various sci-fi films involving numerous similar looking individuals with the same exact personality and memories. However, what isn’t known is how human cloning can be viewed in a positive light because of its potential within both reproductive cloning that involves the creation of a new and regenerative medicine also known as therapeutic cloning. It involves cloning […]
Human cloning is a very disputed topic among many individuals living in today’s world. However, the future of it is bright due to the many benefits that it can bring forth. Such as, cures for genetic diseases, prevention and protection against genetic diseases, medical advances, hope for infertile couples, and many other benefits that will be discussed in this essay. According to Manipulating the Human Genome by Jill U. Adams, genetic manipulation of human embryos is prohibited by 29 countries, […]
Human cloning is a widely controversial topic to people who do not fully understand the science behind cloning as most people have an ethical issue with cloning a human. While it is called human cloning it is not the process of completely cloning a full body human. Cloning for medical purposes includes being able to clone fully functional stem cells that are used to build, maintain and repair the human body throughout our entire lives. It is even possible for […]
Animal testing has been a part of pharmaceutical, cosmetic, and toxicity research for many years. Many innocent animal lives are being taken for the sake of science, when it is unnecessary to do so. Scientists have had the knowledge of human embryonic stem cells for research for years and yet they decide to use sentient animals instead. Even though animal testing has proven beneficial in the past, scientists should use human embryonic stem cells to do research instead of animals […]
HYDROGELS FOR WOUND HEALING APPLICATIONS Abstract This chapter discusses about the hydrogels both natural and synthetic that can be used for wound healing applications. Also it discusses briefly about the various novel techniques that have been developed recently. Keywords: Hydrogels; Chitosan, Antimicrobial; Grafting; Blending; Wound dressing; Wound healing; Gene therapy, Stem cell therapy, Skin Engineering, pH and Thermosensitive polymers. 1 Introduction Healthcare is an essential aspect of human survival. So many biopolymers have generated interest in a number of biomedical […]
