Anatomy: Becker’s Muscular Dystrophy

The disease Becker’s Muscular Dystrophy was named after doctor Peter Emil Becker from Germany because he described the Duchenne Muscular Dystrophy. It is unknown who first obtained the disease but usually teens or young adults are most likely to get the Becker’s Muscular Dystrophy . The disease is caused by a deformity caused by the X chromosome which the women hold,then it produces a protein dystrophia which causes the muscle fibers to weaken and even disappear. Some of the symptoms of Becker’s Muscular Dystrophy which eighty to ninety nine percent of people with the disease have urine looking irregular, hard time walking up the stairs, high level of blood creatine phosphokinas, not wanting to exercise,and myalgia which is muscle ache. More awful symptoms people with Becker’s Muscular Dystrophy is feeling tired, muscle cramps, high liver enzymes, and pes plants which cause your bottom of your foot to be flat due to muscle loss. The disease was not discovered by a scientist it was discovered by Peter Emil Becker who was named by the muscular disease.

There is no cure for Becker’s Muscular Dystrophy but they have different ways to treat the patient by remaining to exercise to keep the muscles in motion, physical therapy, genetic counseling such as using catabolic steroids, a person with the disease in the future may need a wheelchair, a occupational therapy to help them go to the bathroom and other daily activities we do, speech therapy which will be need towards the ending of life to eat only certain foods in a proper position, and recreational therapy to get help to be involved in entertaining activities. They are working towards having a gene therapy to hopeful help with the deformity of the X chromosome to help them recovery from Becker’s Muscular Dystrophy. They are doing a study on about the micro-macroscopic effects on muscle to see if this certain medicine going to be utilized for Becker’s Muscular Dystrophy to see if it is safe the medicine is called givionstat and placebo for a year with fourth eight people. But they had to stop the study because it had a terrible effect of diarrhea. Givionstat is a drug that could help being a anti inflammatory, anti angiogenic,and antineoplastic activities. Placebo is a pill that is to fool the patients in a clinical trial because the pill is really filled with no medicine. Other ways to help with this disease is by gene replacement, gene modification, stem cells, using the proteins myostatin and utrophin to help strength the muscle, and also help produce blood flow through out the muscles.

The disease is mostly found in younger adults and in people in there early twenties. It causes muscle weakness usually in legs and pelvis which can affect your walking, cause many people to fall, and do any other physical activities such as running or playing jump rope. Becker’s Muscular Dystrophy also affects the muscle of the heart by the muscle mass decrease causing it hard to have blood pump through the heart. Even in the lungs it could cause a decreased amount of muscle mass which could lead to having a hard time breathing. As seen above the heart and lung mass when decreased could lead to huge issues that you would need to go to the emergency room for or even lead to death. The back can be affected by the disease causing scoliosis which is causing the spine to curve.

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