Synthesis of New Solid Forms of Bumetanide and their Characterization
1. INTRODUCTION Bumetanide (BUM) is a loop diuretic of the sulfamyl category, (3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid) most often used to treat heart failure. Most often used in the people whom high dose of furosemide or other diuretics are ineffective. The main differences between bumetanide and furosemide are the bioavailability and potency. Mostly 60 percent of furosemide is […]
